Monthly Archives: March, 2013

What Kind of Mother?

Toni Ingram sent an abuse complaint to Photobucket to have her daughter’s content removed from the memorial site I set up.

I received this via email yesterday.

————————————————————————————

Abuse (Photobucket Support)

Mar 27 11:52 am (MDT)

Hello.
This is to notify you that we have received notice that the following material posted by you via the Photobucket service is infringing:

http://s1301.photobucket.com/user/Remembering_Morgan/library/In%20Memory%20of%20Morgan/ 293 images

In response, we have removed such material from the Photobucket service. Such material will remain unavailable from the Photobucket service unless you provide us with a completed copy of the following Counter Notice to Photobucket’s Designated Copyright Agent:

COUNTER NOTICE

1. Identification of the material that has been removed or to which access has been disabled on the Photobucket service and the location at which the material appeared before it was removed or access to it was disabled:

2. I hereby state under penalty of perjury that I have a good faith belief that the material was removed or disabled as a result of mistake or misidentification of the material to be removed or disabled.

3. Your name, address, telephone number and, if available, email address:

4. I hereby state that I consent to the jurisdiction of the Federal District Court for the judicial district in which my address is located or, if my address is outside of the United States, for any judicial district in which Photobucket may be found, and I will accept service of process from the complaining party who notified Photobucket of the alleged infringement or an agent of such person.

5. Your physical or electronic signature (full legal name):____________________________
The Counter Notice should be delivered to the following Designated Copyright Agent of Photobucket:

PLEASE NOTE: Further notifications of copyright violations posted in this Photobucket account may result in the banning of this account.

Designated Copyright Agent
Photobucket Corp.
http://photobucket.com
PO Box #13003
Denver, CO 80201
abuse@photobucket.com
Fax: 303.395.1165

——————————————————————————————————

Poor Morgan!  I can’t imagine what it must have been like to live with someone so controlling.  Even in death Toni can’t let Morgan be her own person.

If Morgan was a minor this would be a non-issue.  But Morgan was not a minor.  Morgan Ingram was an adult. Her Photobucket was public.  If she wanted her content censored she would have censored it herself.

I hope you have a lot of time on your hands Toni.  There are plenty of photo and file sharing sites on the web and I plan to visit every one of them.

Advertisements

The Many Faces of Toni Ingram

Jodin’s “fiance” has magically morphed into Morgan’s former boyfriend?

Jodin Does My Death Space

This is too funny.  I can’t wait for Jodin to come out to the My Death Space crowd.

Looks Like I Struck a Nerve in Montana or Colorado

Thank you for providing the doctors names.  You can bet I will be contacting every one of them to confirm they are acting as consultants to the Ingrams.

Oh by the way, I’ve never lived in a trailer park but I don’t look down on those who do.  I have a high school diploma, not a GED, but again, I don’t look down on people who had to go that route for whatever reason.  Morgan Ingram was a non-traditional student and GED recipient if I recall.

I have never nor would ever “dub myself as smart.”  Intelligence (or lack of) is obvious.  People will make that determination based on what they are shown, not what they are told..

What Dr. Kurtzman Knew

March 27, 2013

I apologize for not posting this on the date promised, real life got in the way.

————————————————-

In her blog Toni Ingram has consistently criticized Dr. Robert Kurtzman for conclusions he reached in the autopsy of Morgan Ingram.  Toni has claimed on more than one occasion that retired medical examiners, two forensic pathologists, doctors, specialists, and a pharmaceutical scientist have all contacted her to let her know that Dr. Kurtzman should have known right away that the level of amitriptyline found in Morgan’s blood was lethal.   Apparently Toni expects readers to believe members of the medical community would criticize one of their own for not jumping to an immediate conclusion and exercising too much caution.  Although I don’t believe Toni I was curious why Dr. Kurtzman did not rule Morgan’s death a suicide from the very beginning.  Did Dr. Kurtzman know something we don’t?  Could death by amitriptyline intoxication be more complex than Toni Ingram would like her readers to believe?  The answers required research.

As I began researching Amitriptyline it became evident to me that information from the Morgan’s Stalking blog contradicted my research.  I will note these contradictions as they occur.

So what exactly is amitriptyline?

Amitriptyline is a disturbingly effective killer; a chemical perfect storm for the suicidal.  It is an extremely complex medication originally approved by the U.S. Food and Drug Administration to treat various forms of depression.  It also has several off-label uses (off-label means not FDA approved) such as treatment of neuropathic pain, and migraine prophylaxis.  Amitriptyline is a tricyclic, antidepressant, so-called because of its three-ring chemical structure.  It is the most frequently abused/misused of the tricyclic antidepressants.  In a review of 165 persons with tricyclic poisonings admitted to one hospital in a two year period, 62% involved amitriptyline.

Amitriptyline is readily absorbed from the gastro-intestinal tract, with peak plasma concentrations occurring within a few hours of oral administration (contradicts MS blog, “She would have to have been given this stuff between noon and nine pm-ish for that high of a levelSeptember 15, 2012  http://morganingram.com/wordpress/?p=1207 )

It is highly lipid soluble meaning it is stored by fat cells and not released until the body exhausts the rest of the dose.Peak drug concentrations occur early and this is the reason why most deaths from poisoning occur outside the hospital.

Amitriptyline undergoes extensive first-pass metabolism and is demethylated in the liver to its primary active metabolite, nortriptyline. Amitriptyline is widely distributed throughout the body and is extensively bound to plasma and tissue protein.

AMI is a mild antiemetic (prevents vomiting) and in fact is used successfully to treat a condition called Cyclic Vomiting Syndrome. (contradicts MS “did not regurgitate any of them back up, as is most common with Amitriptyline” and ”A research scientist and doctor who works at a pharmaceutical company has assured us there is no way Morgan could ingest enough Amitriptyline to produce that level without vomiting it up. It can’t happen” March 12, 2013 http://morganingram.com/wordpress/?p=3198).

Amitriptyline is anticholinergic and therefore will inhibit parasympathetic nerve impulses by blocking acetylcholine. Acetylcholine is a vital neurotransmitter that is released at the ends of nerve fibers in the somatic and parasympathetic nervous systems and transmits nerve impulses across a synapse.  The nerve fibers of the parasympathetic system are responsible for the involuntary movements of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, etc.  This is why Morgan developed pulmonary edema, not because  her heart stopped for only a few seconds, then her lungs would have automatically filled up with fluid and this would have been enough to kill her,”  March 26, 2013  http://morganingram.com/wordpress/?p=3386

The anticholinergic effect is exponential to the amount of the drug consumed. To put it plainly, amitriptyline slows down vital body functions, including significant reduction in gastrointestinal mobility.This results in a prolonged period of absorption.

If all this was not enough, amitriptyline and its active metabolite nortriptyline are subject to enterohepatic recirculation.  This means it is secreted into bile which is held by the gall bladder and dumped back into the small intestine creating an efficient deadly cycle.

Amitriptyline has a narrow therapeutic index, meaning there is a fine line between a therapeutic and toxic dose.  A lethal dose can be as low as 5mg/kg.  Morgan Ingram weighed 115 lbs. or 52.1 kg., so theoretically a fatal dose could have been as low as 260.5 mg or approx. 10 25 mg pills.  The fact that such a small amount could be fatal is another unique characteristic of amitriptyline (contradicts MS “18 – 25mg pills is 450 mg., simple math 18 X 25 = 450.  And it is not a lethal dose, yes you read that right, 450 mg. is not a lethal dose.  Once again I welcome you to find a qualified expert who will testify that 450 mg. of Amitriptyline is a lethal dose” March 15, 2013  http://morganingram.com/wordpress/?p=3272

Any “qualified expert” could tell Toni Ingram the most frightening fact about amitriptyline is scientists do not know how it will behave from one patient to the next due to a high degree of genetic variability in the specific liver enzymes that process the drug.  A lethal amount for one person might have little effect on another.  Depending on the genetic variant, the liver enzyme that processes amitriptyline, known as CYP2D6, will metabolize in one of the following ways:

Poor metabolizer–these subjects have little or no CYP2D6 function

Intermediate metabolizers–these subjects metabolize drugs at a rate somewhere between the poor and extensive metabolizers,

Extensive metabolizer–these subjects have normal CYP2D6 function

Ultra rapid metabolizer–these subjects have multiple copies of the CYP2D6 gene expressed, and therefore greater-than-normal CYP2D6 function

The only way to know which variant a patient will express, other than trial and error, is to run a plasma concentration assay.

——————————————————-

In light of this drug’s many complexities, I hope it’s obvious to readers why Dr. Kurtzman didn’t immediately and carelessly blame amitriptyline for Morgan’s death.  Given Toni Ingram’s previous track record for omitting facts that undermine her version of the “truth,” I don’t think I’m off base suggesting we don’t have the entire story.  I strongly suspect Dr. Kurtzman told the Ingrams he was issuing a tentative death certificate per legality, but cause and manner could change as pending reviews and results became available.

By gaining a greater understanding of amitriptyline I unintentionally gained a greater understanding of Toni Ingram.  I believe the numerous unnamed medical experts and their opinions of Dr Kurtzman are fabrications born out of desperation.   In my opinion this woman is so arrogant, so convinced of her superiority she didn’t even bother to research how amitriptyline is processed.  I don’t think it occurred to her that anyone would question what she says.

Toni knows Keenan Vanginkel and Brooke Harris will never be charged with murder.  The alleged evidence consists of hearsay and lies and the visions of psychics and pet communicators.  There is no chain of custody for the alleged physical evidence.

There is no cover-up being perpetrated by the police or the forensic pathologist. Why would they risk their careers to protect Keenan?  He’s a kid who works at a grocery store.  He doesn’t have any connections or know anyone with political clout.

Toni Ingram knows this but she will never accept it.

——————————————————

Toni Ingram, full credit for italicized quotes, 2012-2013 Morgan’s Stalking, http://morganingram.com/wordpress/

Gergov, Merja, et al. “CYP2D6 and CYP2C19 genotypes and amitriptyline metabolite ratios in a series of medicolegal autopsies.” Forensic Science International 10 May 2006: 177+. Academic OneFile. Web. 15 Mar. 2013.

Bachofer, Julia, et al. “Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy.” Clinical Chemistry 51.2 (2005): 376+.

Academic OneFile. Web. 15 Mar. 2013

/CASE REPORTS/ In a case of acute overdosage (225 mg) a patient in light coma had temporary complete oculomotor paresis, unresponsive to caloric stimulation or doll’s head maneuvers.

[Grant, W.M. Toxicology of the Eye. 3rd ed. Springfield, IL: Charles C. Thomas Publisher, 1986., p. 85] **PEER REVIEWED**

/CASE REPORTS/ A 34-yr-old man … suffered from severe adverse effects during treatment with amitriptyline, 50 mg/day. It was subsequently shown that the patient was a slow metabolizer of amitriptyline. However, he tolerated a dose of 200 mg of imipramine/day, which was necessary in order to reach a therapeutic level of about 900 nM for imipramine plus desipramine.

[Broson K et al; Ther Drug Monit 13 (2): 177-82 (1991)] **PEER REVIEWED** PubMed Abstract

———————————————————————————-

Edits:

     March 29, 2013 2:54 P.M.- Grammar

     April  2, 2013  3:16 P.M – Added and corrected attributions.

Whereabouts Still Unknown

Exploring new avenues in the search for missing persons

HardballTalk

Baseball. Baseball. And then a bit more baseball.

Book Journey

Continuing adventures of a true bookaholic...

Debunking Denialism

Fighting pseudoscience and quackery with reason and evidence.

Michigan is Amazing

Showing the world that Michigan is Amazing!

TED Blog

The TED Blog shares interesting news about TED, TED Talks video, the TED Prize and more.

The Context Of Things

Ted Bauer's blog about leadership, marketing, the future of work, and his own misguided life.

Truth For Morgan Too

TFM Tumblr On Wordpress

Steve Huff's Blog

Current events, history, and other bad ideas, from an unreliable narrator (formerly known as HuffWire)

Meg Investigates

Exploring Life off the Beaten Path